{"id":1388,"date":"2020-02-25T23:35:05","date_gmt":"2020-02-25T22:35:05","guid":{"rendered":"http:\/\/www.cisztasfibrozis.hu\/?p=1388"},"modified":"2020-07-27T10:55:20","modified_gmt":"2020-07-27T08:55:20","slug":"a-cff-tamogatja-a-nem-sertes-eredetu-enzim-terapia-kifejleszteset","status":"publish","type":"post","link":"https:\/\/www.cisztasfibrozis.hu\/index.php\/2020\/02\/25\/a-cff-tamogatja-a-nem-sertes-eredetu-enzim-terapia-kifejleszteset\/","title":{"rendered":"A Cystic Fibrosis Foundation t\u00e1mogatja a nem sert\u00e9s eredet\u0171 enzimter\u00e1pia kifejleszt\u00e9s\u00e9t"},"content":{"rendered":"\n

Az amerikai Cystic Fibrosis Foundation<\/a> (CFF) meg\u00e1llapod\u00e1st k\u00f6t\u00f6tt a Synspira Therapeutics Inc. nev\u0171 c\u00e9ggel annak \u00e9rdek\u00e9ben, hogy kidolgoz\u00e1sra ker\u00fclj\u00f6n egy nem-sert\u00e9s alap\u00fa enzimp\u00f3tl\u00f3 ter\u00e1pia, amely alternat\u00edv\u00e1t k\u00edn\u00e1lna azon ciszt\u00e1s fibr\u00f3zisos betegek sz\u00e1m\u00e1ra, akiknek a t\u00e1pl\u00e1l\u00e9k megem\u00e9szt\u00e9se gondot okoz.<\/h2>\n\n\n\n

85%- 90% k\u00f6z\u00f6ttire tehet\u0151 ugyanis azoknak a betegeknek az ar\u00e1nya, akiknek el\u00e9gtelen\u00fcl m\u0171k\u00f6dik a hasny\u00e1lmirigye. Ez az\u00e9rt fordul el\u0151, mert a s\u0171r\u0171, ragad\u00f3s hasny\u00e1lmirigy v\u00e1lad\u00e9k akad\u00e1lyozza az enzimek ki\u00fcr\u00fcl\u00e9s\u00e9t, amelyek ahhoz sz\u00fcks\u00e9gesek, hogy az \u00e9telek lebont\u00e1sra ker\u00fcljenek. Fenti enzimek n\u00e9lk\u00fcl a feh\u00e9rje, zs\u00edr, valamint sz\u00e9nhidr\u00e1t nem sz\u00edv\u00f3dik fel az \u00e9telekb\u0151l. Ennek k\u00f6vetkezm\u00e9nye lehet a n\u00f6veked\u00e9sben val\u00f3 visszamarad\u00e1s, gyomor- \u00e9s b\u00e9lrendszeri probl\u00e9m\u00e1k (pl. a g\u00e1zok \u00e9s puffad\u00e1s), valamint az alult\u00e1pl\u00e1lts\u00e1g.<\/p>\n\n\n\n

\"\"
Illusztr\u00e1ci\u00f3
Forr\u00e1s: Pinterest<\/figcaption><\/figure><\/div>\n\n\n\n

Annak \u00e9rdek\u00e9ben, hogy ellens\u00falyozva legyen az enzimhi\u00e1ny, a hasny\u00e1lmirigyel\u00e9gtelens\u00e9gben szenved\u0151 CF betegeknek hasny\u00e1lmirigyenzim p\u00f3tl\u00e1sra van sz\u00fcks\u00e9g\u00fck a legt\u00f6bb \u00e9lelmiszer fogyaszt\u00e1sa k\u00f6zben. <\/p>\n\n\n\n

A Synpira Therapeutics Inc.<\/a> potenci\u00e1lis enzim ter\u00e1pi\u00e1ja az SNSP003 h\u00e1rom, nem \u00e1llati eredet\u0171 enzimet tartalmaz, amelyeknek c\u00e9lja, hogy lebonts\u00e1k a zs\u00edrokat, feh\u00e9rj\u00e9ket, valamint a sz\u00e9nhidr\u00e1tokat (lip\u00e1z, amil\u00e1z, prote\u00e1z).<\/p>\n\n\n\n

Az \u00faj, ciszt\u00e1s fibr\u00f3zis kiv\u00e1lt\u00f3 ok\u00e1t c\u00e9lz\u00f3 kezel\u00e9sek j\u00f3v\u00e1hagy\u00e1s\u00e1nak ellen\u00e9re sok betegnek tov\u00e1bbra is sz\u00fcks\u00e9ge lesz az olyan sz\u00f6v\u0151dm\u00e9nyek kezel\u00e9s\u00e9re, mint p\u00e9ld\u00e1ul a felsz\u00edv\u00f3d\u00e1si zavar. <\/p>\n\n\n\n

Az amerikai CFF elk\u00f6telezetten finansz\u00edrozza a kutat\u00e1sokat a CF sz\u00f6v\u0151dm\u00e9nyek lehets\u00e9ges kezel\u00e9seire, 62,5 milli\u00f3 doll\u00e1rt k\u00f6ltve minderre 2018-ban. T\u00f6bb, mint 15 gy\u00f3gyszer van ut\u00e1np\u00f3tl\u00e1sban, bele\u00e9rtve a potenci\u00e1lis fert\u0151z\u00e9sellenes, gyullad\u00e1scs\u00f6kkent\u0151, v\u00e1lad\u00e9kold\u00f3 ter\u00e1pi\u00e1kat \u00e9s t\u00e1pl\u00e1lkoz\u00e1si hat\u00f3anyagokat is.<\/p>\n\n\n\n

Ford\u00edtotta: Borb\u00edr\u00f3 Brigitta
Forr\u00e1s: CFF.org<\/a> 2020.02.12
<\/p>\n\n\n\n

Vissza a f\u0151oldalra<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Az amerikai Cystic Fibrosis Foundation (CFF) meg\u00e1llapod\u00e1st k\u00f6t\u00f6tt a Synspira Therapeutics Inc. nev\u0171 c\u00e9ggel annak \u00e9rdek\u00e9ben, hogy kidolgoz\u00e1sra ker\u00fclj\u00f6n egy nem-sert\u00e9s alap\u00fa enzimp\u00f3tl\u00f3 ter\u00e1pia, amely…<\/p>\n","protected":false},"author":2,"featured_media":1422,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[67,33,77,76],"class_list":["post-1388","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cikkek","tag-cff","tag-cisztas_fibrozis","tag-cystic-fibrosis-foundation","tag-enzimpotlas","entry","double"],"_links":{"self":[{"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/posts\/1388","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/comments?post=1388"}],"version-history":[{"count":11,"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/posts\/1388\/revisions"}],"predecessor-version":[{"id":1407,"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/posts\/1388\/revisions\/1407"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/media\/1422"}],"wp:attachment":[{"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/media?parent=1388"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/categories?post=1388"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cisztasfibrozis.hu\/index.php\/wp-json\/wp\/v2\/tags?post=1388"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}